Strain segmentario y longitudinal de pacientes cubanos con drepanocitosis

Angela Jacqueline Torres Zambrano, Danny Fernando Montenego Tobar, Liudmila Borges Borges Moreno

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Resumen

Introducción: Las strain segmentaria y longitudinal constituyen excelentes parámetros para la cuantificación de la contractilidad miocárdica.

Objetivo: Identificar los valores de strain segmentario y longitudinal de pacientes cubanos con drepanocitosis.

Material y Método: Estudio descriptivo prospectivo en los 31 pacientes con drepanocitosis y 52 controles que asistieron al Instituto de Cardiología y Cirugía Cardiovascular entre junio de 2017 a enero de 2018, a los que se determinó strain segmentario y longitudinal como variables de estudio. Se compararon medias mediante la prueba t de Student y se realizó un análisis de varianza (ANOVA) con una prueba a posteriori de Tukey para p<0,05.

Resultados: En los drepanocíticos las medias de strain segmentario estuvieron entre -17,7±3,4 % (p=0,0001*) y -28,6±4,1 % (p=0,0005*) y -29,3±1,1 % (p=<0,0002*), fueron homogéneos todos sus segmentos y en el grupo control entre -19,3±2,9 % (p=0,0001*), en general. Independientemente de que en los pacientes drepanocíticos las medias fueron más bajas estuvieron en el rango de lo normal. Los valores de las medias de strain longitudinal global oscilaron entre -19,2±3,3 y -25,2±2,7 fueron más negativos en el grupo control, respecto a los cubanos con drepanocitosis.

Conclusiones: Los resultados obtenidos son los primeros de su tipo publicados en Cuba. Las strain segmentaria y longitudinal de los pacientes drepanocíticos cubanos analizados, con resultados significativamente diferentes que los individuos sanos, pero normales, coinciden con lo informado en la literatura internacional.

Palabras clave

drepanocitosis, strain segmentaria, strain longitudinal.

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