Holistic view of new challenges: technological paradigms and bioethical basis of Futuristic Medicine
Abstract
Introduction: Medicine in the 21st century will be a fusion point of numerous new technologies. Changes in the paradigms of medical attention will emerge.
Objective:To present a view of what future medical attention could be.
Material and methods:A review of the last and new technological tools at the service of Medicine is made, and their possible transformations and future implementation are studied through the search of the main databases of the data indexed during the last seven years, which will make a change in the scientific thought and a predictive view of the medical attention worldwide, and make reflections on the medical approaches that arise from translational medicine. The role of nanotechnology in the futuristic pharmacology is analyzed, as well as genetics and robotics; and comparisons are made regarding the amount of research by countries and the current condition in Latin America, and the way the new scientific innovations will influence in the Bioethics, which could give rise to transhumanism.
Results:The influence of the new technologies is linked to the economic and social development. Therefore, its implementation will not be equitable, existing an important difference in establishment of patents, indexed research, and quotations between developed and underdeveloped countries, where no Latin American country is among the 10 first places in the world ranking.
Conclusions:Current technology gives solution to some problems, but it has not been able to be acquainted with many diseases. The use of nanotechnology, genetics, and robotics will provoke changes in the confrontation paradigms of diseases, which could cause dehumanization and bioethical issues.
Keywords: Biotechnology, nanotechnology, genetics, bioethics.
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REFERENCIAS BIBLIOGRÁFICAS
1. Hood, L. & Flores, M. A personal view on systems medicine and the emergence of proactive P4 medicine: predictive, preventive, personalized and participatory. New Biotechnology 2012; 29(6): 613-624. Disponible en: http://dx.doi.org/10.1016/j.nbt.2012.03.004
2. Becú-Villalobos, Damasia. Medicina traslacional, ¿moda o necesidad? Medicina (Buenos Aires) 2014; 74(2): 170-172. Disponible en: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0025-76802014000200018&lng=es&tlng=es
3. Suzuki, R., Omata, D., Oda, Y., Unga, J., Negishi, Y., Maruyama, K. Cancer therapy with nanotechnology-based drug delivery systems: applications and challenges of liposome technologies for advanced cancer therapy.Nanomaterials in Pharmacology 2016; 457-482. Disponible en: http://link.springer.com/protocol/10.1007/978-1-4939-3121-7_23
4. Quero, S., Párraga-Niño, N., García-Núñez, M., Sabrià, M. . Proteómica en enfermedades infecciosas. Enfermedades Infecciosas y Microbiología Clínica 2016; 34(4): 253-260.
5. Krause Bernardo J, Castro-Rodríguez José A., Uauy Ricardo, Casanello Paola. Conceptos generales de epigenética: proyecciones en pediatría. Rev. chil. pediatr. [Internet]. 2016 Feb [citado 2017 Ene 10] ; 87( 1 ): 4-10. Disponible en: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0370-41062016000100002&lng=es. http://dx.doi.org/10.1016/j.rchipe.2015.12.002.
6. Díaz Fernández Usnavia, Rodríguez Ferreiro Annarli Olivia. Biotechnology uses in the development of personalized medicine. MEDISAN [Internet]. 2016 Mayo [citado 2017 Ene 10] ; 20( 5 ): 678-687. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1029-30192016000500013&lng=es.
7. Konishi, H., Ichikawa, D., Arita, T., Otsuji, E. Microarray Technology and Its Applications for Detecting Plasma microRNA Biomarkers in Digestive Tract Cancers. Microarray Technology: Methods and Applications 2016: 99-109.
8. Rodrigues, J., Paulovich, F., de Oliveira, M., de Oliveira, O. On the convergence of nanotechnology and Big Data analysis for computer-aided diagnosis. Nanomedicine 2016; 11(8): 959-982. Disponible en: http://dx.doi.org/10.2217/nnm.16.35
9. Aguirre Fernández RE, Serra Valdes MA, Chiliquinga Villacís SI, Agudo Gonzabay BM, Arciniega Jacome LA. Visión integradora del pase de visita médico asistencial y docente en hospitales universitarios de Ecuador.. Revista Habanera de Ciencias Médicas [revista en Internet]. 2016 [citado 2017 Ene 10];15(6):[aprox. 0 p.]. Disponible en: http://www.revhabanera.sld.cu/index.php/rhab/article/view/1263
10. Daraee, H., Etemadi, A., Kouhi, M., Alimirzalu, S., Akbarzadeh, A. Application of liposomes in medicine and drug delivery. Artificial cells, nanomedicine, and biotechnology 2016; 44(1): 381-391.
11. Quintili, Mario. Nanociencia y Nanotecnología... un mundo pequeño. Cuadernos del Centro de Estudios en Diseño y Comunicación. Ensayos 2012; 42: 125-155. Disponible en:http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1853-35232012000400010&lng=es&tlng=es
12. Valdes, R., Yin, D. T. Fundamentals of Pharmacogenetics in Personalized, Precision Medicine. Clinics in Laboratory Medicine 2016; 36(3): 447-459. Disponible en: http://dx.doi.org/10.1016/j.cll.2016.05.006
13. Hernández Betancourt Jenny de la Caridad, Serrano Barrera Orlando. La medicina personalizada, la revolución genómica y el Sistema Nacional de Salud. Rev Cubana Salud Pública [Internet]. 2014 Dic [citado 2017 Ene 10] ; 40( 4 ): 379-391. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864-34662014000400012&lng=es.
14. Bernales, Margarita, Cabieses, Báltica, Obach, Alexandra, Maturana Andrés. Investigación traslacional en salud: un camino para la investigación pragmática e interdisciplinaria. Revista médica de Chile 2015; 143(1): 128-129. Disponible en: https://dx.doi.org/10.4067/S0034-98872015000100020
15. Krause, Bernardo J, Castro-Rodríguez, José A., Uauy, Ricardo, Casanello, Paola. Conceptos generales de epigenética: proyecciones en pediatría. Revista chilena de pediatría 2016; 87(1):4-10. Disponible en: https://dx.doi.org/10.1016/j.rchipe.2015.12.002
16. Saldívar-González, F., Prieto-Martínez, F. D.,Medina-Franco, J. L. Descubrimiento y desarrollo de fármacos: un enfoque computacional. Educación Química 2016. http://dx.doi.org/10.1016/j.eq.2016.06.002
17. Aoki, Y., Sundqvist, M., Hooker, A. C., Gennemark, P. PopED lite: an optimal design software for preclinical pharmacokinetic and pharmacodynamic studies. Computer methods and programs in biomedicine 2016; 127: 126-143.
18. Pers, T. H. Gene set analysis for interpreting genetic studies. Human Molecular Genetics 2016: ddw249. doi:10.1093/hmg/ddw24. http://hmg.oxfordjournals.org/citmgr?gca=hmg%3Bddw249v2
19. Schukur, L. & Fussenegger, M. Engineering of synthetic gene circuits for (re-)balancing physiological processes in chronic diseases. Wires Syst Biol Med 2016; 8(5): 402-422. http://dx.doi.org/10.1002/wsbm.1345
20. Aalaei, S., Shahraki, H., Rowhanimanesh, A., Eslami, S. Feature selection using genetic algorithm for breast cancer diagnosis: experiment on three different datasets. Iranian Journal of Basic Medical Sciences 2016; 19(5): 476-482.
21. James, R. A., Campbell, I. M., Chen, E. S., Boone, P. M., Rao, M. A., Bainbridge, M. N., Shaw, C. A. A visual and curatorial approach to clinical variant prioritization and disease gene discovery in genome-wide diagnostics. Genome Medicine 2016; 8(1): 13.
22. Jeong, W., Kumar, R., Menon, M. Past, present and future of urological robotic surgery. Investigative and clinical urology 2016; 57(2): 75-83.
23. Bravo, R., Arroyave, M. C., Trépanier, J. S., Lacy, A. M. Robotics in General Surgery: Update and Future Perspectives. Advances in Robotics & Automation, 2016.
24. . Stefanidis D, Wang F, Korndorffer JJ, Dunne JB, Scott DJ. Robotic assistance improves intracorporeal suturing performance and safety in the operating room while decreasing operator workload. Surg Endosc 2010; 24: 377-82. doi:10.1007/s00464-009-0578-0
25. Bernier, G. V., Sanchez, J. E. Surgical simulation: the value of individualization. Surgical endoscopy 2016; 30(8): 3191-3197.
26. Ledford, Heidi. "UK Bioethicists Eye Designer Babies And CRISPR Cows". Nature.com. N.p., 2017. Web. 23 Jan. 2017. Available from: https://scholar.google.com/scholar?hl=es&q=UK+bioethicists+eye+designer+babies+and+CRISPR+cows&btnG=&lr=
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