Factors associated with complications in patients with pancreatic pseudocyst. “Arnaldo Milián Castro” University Hospital, 2013-2017
Keywords:
Pancreatic pseudocyst, pancreas, pancreatic cysts.Abstract
Introduction: Pancreatic pseudocysts represent the most common cystic lesions of the pancreas. They are complications of acute and chronic pancreatitis although there are other less frequent causes such as pancreatic trauma.
Objective: To identify the influence of clinical and morphological factors involved in the evolution of patients.
Material and Methods: An observational longitudinal analytical cohort study was conducted in patients with pancreatic pseudocysts treated at “Arnaldo Milián Castro” University Hospital from 2013 to 2017.
Results: Pancreatic pseudocyst predominated in the male sex and in the age group between 40 and 60 years old (55 %) for both sexes in the sample studied; the median age was 53 years. We identified the following risk factors for the development of complications: acute pancreatitis as a cause (OR = 2,377-CI: 0,566-9,977), time of formation shorter than six weeks (OR = 2,333-CI: 0,373-14,613) and size smaller than six cm (OR = 1,800-IC: 0.259-12.502).
Conclusions: Patients over the age of 53 years, male sex, and size less than six cm had a higher relative risk of death. The risk factors for complications identified were acute pancreatitis, formation before six weeks, and size less than six cm. The time of formation and persistence of pseudocysts were longer in patients with complications, unlike the size that registered greater value for patients without complications.
Downloads
References
1. Luis Martínez-Ordaz J, Toledo-Toral C, Franco-Guerrero N, Tun-Abraham M, Manuel Souza-Gallardo L. Tratamiento quirúrgico del seudoquiste de páncreas. Cir Cir [Internet]. 2016 [citado 25/02/2018];84(4):[288-92]. Disponible en: https://www.sciencedirect.com/science/article/pii/S0009741115002297
2. Hao L, Pan J, Wang D, Bi YW, Ji JT, Xin L, et al. Risk factors and nomogram for pancreatic pseudocysts in chronic pancreatitis: A cohort of 1998 patients. J Gastroenterol Hepatol [Internet]. 2017 [cited 03/02/2018]; 32(7):[1403-11]. Abalilable from: https://onlinelibrary.wiley.com/doi/pdf/10.1111/jgh.13748
3. Gurusamy KS, Pallari E, Hawkins N, Pereira SP, Davidson BR. Management strategies for pancreatic pseudocysts. Cochrane Database Syst Rev [Internet]. 2016 [cited 03/02/2018]; 4:[aprox.68.p]. Abalilable from: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD011392.pub2/abstract
4. Services USNLoMDoHaH, Health NIo. Seudoquiste pancreático. [Internet]. 2018. [citado 28/02/2018]. Disponible en: https://medlineplus.gov/spanish/ency/article/000272.htm
5. Muñoz L, Vélez J, Molano D, Susunaga P, Gómez M. Seudoquiste pancreático infectado por Shewanella putrefaciens: reporte de caso. [Internet]. 2015 [citado 3/02/2018];19(4):[179-82]. Disponible en: https://www.sciencedirect.com/science/article/pii/S0123939214000666
6. Alhassan S, Umar S, Lega M. One of the Largest Pancreatic Pseudocysts in the Literature: A Case Report. Cureus [Internet]. 2017 [cited 01/02/2018];9(7):[aprox.4.p]. Abalilable from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606714/pdf/cureus-0009-00000001493.pdf
7. Crisanto-Campos BA, Arce-Liévano E, Robles-Aviña JA, Cárdenas-Lailson LE, Trejo-Ávila ME, Moreno-Portillo M. Experiencia inicial en pancreatoduodenectomía laparoscópica en un hospital general de la Ciudad de México. Cir Gen [Internet]. 2016 [citado 29/02/2018];38:[59-66]. Disponible en: https://www.medigraphic.com/pdfs/cirgen/cg-2016/cg162b.pdf
8. Fallas Durón LE. Pseudoquiste pancreático. Revista medica de costa rica y centroamerica [Internet]. 2013 [citado 29/02/2018];70(605):[87-93]. Disponible en: https://www.medigraphic.com/pdfs/revmedcoscen/rmc-2013/rmc131q.pdf
9. Dabkowski K, Bialek A, Kukla M, Wojcik J, Smereczynski A, Kolaczyk K, et al. Mediastinal Pancreatic Pseudocysts. Clin Endosc [Internet]. 2017 [cited 01/02/2018];50(1):[76-80]. Abalilable from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299981/pdf/ce-2016-089.pdf
10. Guardado F AAJ, Ardisson F J, Guerrero, L A, Villanueva E, Gómez N. Pseudoquiste pancreático. Revisión y reporte de caso. (Spanish). [Internet]. 2014 [citado 02/02/2018];82:[425-31]. Disponible en: https://www.redalyc.org/pdf/662/66231427010.pdf
11. The Cleveland Clinic. Center for Consumer Health Information. [Internet]. Quistes y Pseudoquistes Pancreáticos. New York State: Department of Health. 2018 [cited 27/02/2018]. Abalilable from: http://www.clevelandclinic.org/health/sHIC/html/s14627.asp
12. Nuria Martínez Sanz FMGV, María Vicente Ruiz, Patricia Pastor Pérez, Miguel Ruiz Marín, Antonio Albarracín Marín-Blázquez. Pseudoquiste pancreático de localización intrahepática. Rev esp enferm dig [Internet]. 2015 [citado 09/03/2018];107(4):[247-8]. Disponible en: http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082015000400019
13. Iglesias MJ. Comportamiento del Pseudoquiste Pancreático en el Hospital Universitario “General Calixto García Íñiguez” enero 2005-abril 2008 [Tesis de Terminacion de Especialidad]. Publicado en: Biblioteca Virtual de salus/Cirured; 2008. p.43 Disponible en: http://www.sld.cu/galerias/pdf/uvs/cirured/tesis.pdf
14. Argente del Castillo Sánchez T, Aguilera Tapia B. Hemoperitoneo espontáneo secundario a rotura de pseudoquiste pancreático: una causa inusual de muerte inesperada. Gac int cienc forense [Internet]. 2015 [citado 25 feb 2018];(15):20-6 Disponible en: https://core.ac.uk/download/pdf/71042188.pdf
15. Santiago F, Tadeo Aguilar A, González G, Sánchez-Valdivieso ea. Pseudoquiste pancreático post-traumático en tauromaquia. Rev Chil Cir [Internet]. 2016 [citado 03/02/2018];68(2):[173-5]. Disponible en: https://scielo.conicyt.cl/pdf/rchcir/v68n2/art11.pdf
16. Gutiérrez SR. Pseudoquiste Pancreatico. Rev Med de Costa Rica Y Centroamerica [Internet]. 2014 [citado 22/02/2018];71(610):[313-6]. Disponible en: http://www.medigraphic.com/pdfs/revmedcoscen/rmc-2014/rmc142zb.pdf
17. MINSAP. Dirección de Registros Médicos y Estadísticas de Salud. [Internet]. La Habana: MINSAP. 2017. Anuario de Salud del 2016. [citado 22/02/2018] Disponible en: http://files.sld.cu/dne/files/2017/05/Anuario_Estad%C3%ADstico_de_Salud_e_2016_edici%C3%B3n_2017.pdf
18. Angel Piriz Momblant AHP, Belkis Figueras Torres, Katia Ramírez Sánchez. Seudoquiste del páncreas. Experiencia quirúrgica en 50 casos. Rev Inf Cient [Internet]. 2018 [citado 22/02/2018];97(1):[125-36]. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1028-99332018000100125
19. Simon Bergman WSM. Operative and Nonoperative Management of Pancreatic Pseudocysts. Surg Clin N Am [Internet]. 2007 [cited 10/03/2018];87:[1447-60]. Abalilable from: https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=1&cad=rja&uact=8&ved=2ahUKEwjavbbmzuXkAhXmmq0KHdfZAAgQFjAAegQIABAB&url=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F18053841&usg=AOvVaw3XK0VT4DHDOUEgEDBYggIg
20. Pan G, Wan MH, Xie KL, Li W, Hu WM, Liu XB, et al. Classification and Management of Pancreatic Pseudocysts. Medicine (Baltimore) [Internet]. 2015 [cited 03/02/2018];94(24):[aprox.5.p]. Abalilable from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616556/pdf/medi-94-e0960.pdf
21. Demeusy A, Hosseini M, Sill AM, Cunningham SC. Intrahepatic pancreatic pseudocyst: A review of the world literature. World J Hepatol [Internet]. 2016 [cited 01/02/2018];8(35):[1576-83]. Abalilable from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5165272/pdf/WJH-8-1576.pdf
22. Rasch S, Notzel B, Phillip V, Lahmer T, Schmid RM, Algul H. Management of pancreatic pseudocysts-A retrospective analysis. PLoS One [Internet]. 2017 [cited 03/02/2018];12(9):[aprox.10.p]. Abalilable from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587297/pdf/pone.0184374.pdf
23. Valverde B. Pancreatic pseudocysts. Gastroenterol Integr [Internet]. 2000 [cited 28/02/2018];1:[341-50]. Abalilable from: http://www.redalyc.org/pdf/3455/345546299011.pdf