Comprehensive neurorestoration in patients with relapsing-remitting multiple sclerosis: a pilot study

Authors

Keywords:

Quality of life, health-related quality of life, multiple sclerosis, relapsing-remitting multiple sclerosis, comprehensive neurorestoration, neurorehabilitation.

Abstract

Introduction: Comprehensive neurorestoration in Multiple Sclerosis improves functional deficits.  The assessment of health-related quality of life, which is a key element for the subjective evaluation of the influences of the current state of health, has been included in the care of people with the disease.

Objective: To determine the influence of comprehensive neurorestoration on the health-related quality of life of patients with relapsing-remitting multiple sclerosis.

Material and Methods: A quasi-experimental study was carried out in 78 patients with relapsing-remitting multiple sclerosis treated at the "Arnaldo Milián Castro" Clinical-Surgical University Hospital in Santa Clara, in the period between January 2014 and December 2020. The patients were randomly assigned to a study group and a control group.

Results: Regarding activities of daily living, the study group showed a mean of 95.89 at the end of the intervention, while the control group showed a mean of 81.28. After the intervention, an improvement in the functioning of the health-related quality of life of the study group was evidenced in the components of the scale, compared with the controls.

Conclusions: It was determined that the development of interventions through comprehensive neurorestoration promote the best possible well-being of patients with relapsing-remitting multiple sclerosis.

Downloads

Download data is not yet available.

References

1. León Cadme MM, Sancan Moreira MT, Cuichán Nuñez DJ. Tratamiento neurorehabilitador integral en pacientes con esclerosis múltiple. Pol Con [Internet]. 2018 [Citado 30/07/2021];3(4):[Aprox. 8 p.]. Disponible en: http://pdfs.semanticscholar.org/6513/1ecc6e60107257048a130463cda87c5a7a54.pdf

2. Gutiérrez Cruz C, Rojas Ruiz FJ, la Cruz Márquez D, Carlos J, Gutiérrez Dávila M. Effect of a combined program of strength and dual cognitive-motor tasks in multiple sclerosis subjects. Int J Environ Res Public Health [Internet]. 2020[Citado 30/07/2021]; 17(17):[Aprox. 12 p.]. Disponible en: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503584/pdf/ijerph-17-06397.pdf

3. Lunde HMB, Assmus J, Myhr K-M, Bø L, Grytten N. Survival and cause of death in multiple sclerosis: a 60-year longitudinal population study. J Neurol Neurosurg Psychiatry [Internet]. 2017 [Citado 30/07/2021];88(8):[Aprox. 5 p.]. Disponible en: http://jnnp.bmj.com/content/88/8/621.abstract

4. Orozco González C, Vagner Ramírez B, Salas Zapata C. Calidad de vida en pacientes con esclerosis múltiple atendidos en una institución de salud de Medellín, Colombia. Univ Salud [Internet]. 2019 [Citado 30/07/2021];21(3):[Aprox. 9 p.]. Disponible en: http://www.scielo.org.co/scielo.php?pid=S012471072019000300226&script=sci_abstract&tlng=en

5. Vázquez Gómez LA, Hidalgo Mesa C, Beltrán González BM, Broche Pérez Y, Mederos Herrera AM. Efectividad de una estrategia para el seguimiento multidisciplinario de pacientes con esclerosis múltiple. EDUMECENTRO [Internet]. 2021 [Citado 30/07/2021];13(4):[Aprox. 8 p.]. Disponible en: http://www.revedumecentro.sld.cu/index.php/edumc/article/view/1887

6. Thompson AJ, Banwell BL, Barkhof F, Carroll WM, Coetzee T, Comi G, et al. Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria. Lancet Neurol [Internet]. 2018 [Citado 30/07/2021];17(2):[Aprox. 50 p.]. Disponible en: http://discovery.ucl.ac.uk/id/eprint/10041020/1/Barkhof_Diagnostic%20criteria_revision%201_final_10OCT2017.pdf

7. Mahoney F, Barthel D. Functional evaluation: the Barthel index. Maryland State Med J [Internet]. 1965 [Citado 30/07/2021];14(2):[Aprox. 4 p.]. Disponible en: http://stopstroke.massgeneral.org/pdfs/barthel_reprint.pdf

8. Kurtzke JF. Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology [Internet]. 1983 [Citado 30/07/2021];33(11):[Aprox. 10 p.]. Disponible en: http://edss.neurol.ru/downloads/Neurology-1983-Kurtzke-1444.pdf

9. Idiman E, Uzunel F, Ozakbas S, Yozbatiran N, Oguz M, Callioglu B, et al. Cross-cultural adaptation and validation of multiple sclerosis quality of life questionnaire (MSQOL-54) in a Turkish multiple sclerosis sample. J Neurol Sci [Internet]. 2006 [Citado 30/07/2021];240(1-2):[Aprox. 4 p.]. Disponible en: http://www.sciencedirect.com/science/article/abs/pii/S0022510X05003448

10. Chaviano Conesa D, Jiménez Martin NM, Pérez Concepción I, Maldonado Gan D, Frómeta Ordúñez R. Beneficio de la neurorrehabilitación integral en pacientes con esclerosis múltiple. Rev Inf Científ [Internet]. 2013 [Citado 30/07/2021];79(3):[ Aprox. 11 p.]. Disponible en: http://revinfcientifica.sld.cu/index.php/ric/article/view/910

11. Marck CH, De Livera AM, Brown CR, Neate SL, Taylor KL, Weiland TJ, et al. Health outcomes and adherence to a healthy lifestyle after a multimodal intervention in people with multiple sclerosis: Three year follow-up. PLoS One [Internet]. 2018 [Citado 30/07/2021];13(5):[Aprox. 13 p.]. Disponible en: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0197759

12. Davies BL, Arpin DJ, Liu M, Reelfs H, Volkman KG, Healey K, et al. Two different types of high-frequency physical therapy promote improvements in the balance and mobility of persons with multiple sclerosis. Arch Phys Med Rehabil [Internet]. 2016 [Citado 30/07/2021];97(12):[Aprox. 8 p.]. Disponible en: http://www.sciencedirect.com/science/article/pii/S0003999316302660

13. Mesa Walwyn IJ, Bravo Acosta T. Influencia del tratamiento neurorrehabilitador en la calidad de vida de pacientes con esclerosis múltiple. Rev Cubana Med Fís Rehabil [Internet]. 2019 [Citado 30/07/2021];10(2):[ Aprox. 13 p.]. Disponible en: http://www.revrehabilitacion.sld.cu/index.php/reh/article/view/293

14. Simpson R, Mair FS, Mercer SW. Mindfulness-based stress reduction for people with multiple sclerosis–a feasibility randomised controlled trial. BMC Neurol [Internet]. 2017 [Citado 30/07/2021];17(1):[Aprox. 12 p.]. Disponible en: http://bmcneurol.biomedcentral.com/articles/10.1186/s12883-017-0880-8

15. Retamal Matus H, Fernández Calderón R, Fernández Elgueta A, Martínez Alarcón C, Montaña Yañez G. Calidad de vida relacionada a la salud de las personas con esclerosis múltiple en la Región de Magallanes, Chile. Rev Chil Salud Pública [Internet]. 2019 [Citado 30/07/2021];23(2):[ Aprox. 8 p.]. Disponible en: http://revistaidiem.uchile.cl/index.php/RCSP/article/view/56345

16. Sandroff BM. Exercise and cognition in multiple sclerosis: the importance of acute exercise for developing better interventions. Neurosci Biobehav Rev [Internet]. 2015 [Citado 30/07/2021];59:[Aprox. 10 p.]. Disponible en: http://www.sciencedirect.com/science/article/pii/S0149763415301810

17. Gich J, Freixanet J, García R, Vilanova JC, Genís D, Silva Y, et al. A randomized, controlled, single-blind, 6-month pilot study to evaluate the efficacy of MS-Line!: a cognitive rehabilitation programme for patients with multiple sclerosis. Mult Scler J [Internet]. 2015 [Citado 30/07/2021];21(10):[Aprox. 12 p.]. Disponible en: http://journals.sagepub.com/doi/abs/10.1177/1352458515572405

Published

2022-09-22

How to Cite

1.
Vázquez-Gómez LA, Hidalgo Mesa C, Broche-Perez Y. Comprehensive neurorestoration in patients with relapsing-remitting multiple sclerosis: a pilot study. Rev haban cienc méd [Internet]. 2022 Sep. 22 [cited 2025 Aug. 3];21(4):e4959. Available from: https://revhabanera.sld.cu/index.php/rhab/article/view/4959

Issue

Section

Clinical and pathological sciences