Risk factors associated with the occurrence of shock in seriously ill patients with the COVID-19
Keywords:
COVID-19, SARS-CoV-2, shock, predictors of COVID-19, creatinine, ischemic heart disease.Abstract
Introduction: The alterations caused by the new coronavirus, as well as other factors such as age, personal pathological history and certain laboratory results, contribute to the state of shock.
Objective: To determine if there is a relationship between the state of shock caused by the COVID-19 infection with the personal pathological history, the INL indices and the qSOFA scale.
Material and Methods: Prospective longitudinal cohort study conducted on 302 patients with a positive diagnosis of COVID-19 who were admitted to Manuel Fajardo Hospital in Havana, Cuba between March and October 2021.
Results: Our results show that 27.8% of the patients evolved to shock, mainly septic shock (25.2%); the median age was 69 years (RIC: 57-77), while the most frequent personal histories were: arterial hypertension (71.5%), obesity (29.5%), and diabetes mellitus (24.8%), respectively. Logistic regression analyses identified the history of heart disease (RR=2.16; (95 % CI: 1.15-4.04; p=0.02) and the creatinine value (RR: 1.01: (95 % CI: 1.00-1.01; p=0, 03) as predictive variables for shock.
Conclusions: The history of ischemic heart disease and the creatinine value represent independent predictive variables for the occurrence of shock; on the other hand, the survival of patients with a positive diagnosis of COVID-19 who develop a state of shock during their hospitalization is significantly lower.Downloads
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